The NetNutritionist Blog

It works 100% of the time to eradicate cancer completely, and cancer does not recur even years later. That is how researchers describe the most convincing cancer cure ever announced.

The weekly injection of just 100 billionths of a gram of a harmless glyco-protein (a naturally-produced molecule with a sugar component and a protein component) activates the human immune system and cures cancer for good, according to human studies among breast cancer and colon cancer patients, producing complete remissions lasting 4 and 7 years respectively. This glyco-protein cure is totally without side effect but currently goes unused by cancer doctors.

Normal Gc protein (also called Vitamin-D binding protein) , an abundant glyco-protein found in human blood serum, becomes the molecular switch to activate macrophages when it is converted to its active form, called Gc macrophage activating factor (Gc-MAF). Gc protein is normally activated by conversion to Gc-MAF with the help of the B and T cells (bone marrow-made and thymus gland-made white blood cells). But, as researchers explain it themselves, cancer cells secrete an enzyme known as alpha-N-acetylgalactosaminidase (also called Nagalase) that completely blocks conversion of Gc protein to Gc-MAF, preventing tumor-cell killing by the macrophages. This is the way cancer cells escape detection and destruction, by disengaging the human immune system. This also leaves cancer patients prone to infections and many then succumb to pneumonia or other infections.

The once-weekly injection of minute amounts of Gc-MAF, just 100 nanograms (billionths of a gram), activates macrophages and allows the immune system to pursue cancer cells with vigor, sufficient to produce total long-term cures in humans.

Nobuto Yamamoto, director of the Division of Cancer Immunology and Molecular Biology, Socrates Institute for Therapeutic Immunology, Philadelphia, Pennsylvania, says this is “probably the most potent macrophage activating factor ever discovered.”

A MACROPHAGE OVERCOMES AND EATS A CANCER CELL.

FROM THE UPJOHN COMPANY, THE IMMUNE SYSTEM

Once a sufficient number of activated macrophages are produced, another Gc-MAF injection is not needed for a week because macrophages have a half-life of about six days. After 16-22 weekly doses of Gc-MAF the amount of Nagalase enzyme fell to levels found in healthy people, which serves as evidence tumors have been completely eliminated. The treatment was fool-proof - - - it worked in 100% of 16 breast cancer patients and there were no recurrent tumors over a period of 4 years, says a report in the January 15 issue of the International Journal of Cancer. [International Journal Cancer.2008 January15; 122(2):461-7]

In another startling follow-up report by Dr. Yamamoto and colleagues, published in the upcoming July issue of Cancer Immunology Immunotherapy, Gc-MAF therapy totally abolished tumors in 8 colon cancer patients who had already undergone surgery but still exhibited circulating cancer cells (metastases). After 32-50 weekly injections, ”all colorectal cancer patients exhibited healthy control levels of the serum Nagalase activity, indicating eradication of metastatic tumor cells,”said researchers, an effect that lasted 7 years with no indication of cancer recurrence either by enzyme activity or CT scans, said researchers. [Cancer Immunology, Immunotherapy Volume 57, Number 7 / July 2008] Published in an early online edition of this journal, this confirming report has received no attention by the new media so far, despite its striking importance.

Gc-MAF treatment for cancer has been agonizingly slow to develop. Dr. Yamamoto first described this immuno-therapy in 1993. [The Journal of Immunology, 1993 151 (5); 2794-2802]

In a similar animal experiment published in 2003, researchers in Germany, Japan and the United States collaborated to successfully demonstrate that after they had injected macrophage activating factor (Gc-MAF) into tumor-bearing mice, it totally eradicated tumors. [Neoplasia 2003 January; 5(1): 32–40]

In 1997 Dr. Yamamoto injected GcMAF protein into tumor-bearing mice, with the same startling results. A single enzyme injection doubled the survival of these mice and just four enzyme injections increased survival by 6-fold. [Cancer Research 1997 Jun 1; 57(11):2187-92]

In 1996 Dr. Yamamoto reported that all 52 cancer patients he had studied carried elevated blood plasma levels of the immune inactivating alpha-N-acetylgalactosaminidase enzyme (Nagalase), whereas healthy humans had very low levels of this enzyme. [Cancer Research 1996 Jun 15; 56(12):2827-31]

In the early 1990s, Dr. Yamamoto first described how the human immune system is disengaged by enzymes secreted from cancer cells, even filing a patent on the proposed therapy. [US Patent 5326749, July 1994; Cancer Research 1996 June 15; 56: 2827-31]

Activated Gc protein has been used in humans at much higher doses without side effect. This Gc macrophage activating factor (Gc-MAF) has been shown to be effective against a variety of cancers including breast, prostate, stomach, liver, lung, uterus, ovary, brain, skin, head/neck cancer, and leukemia.

Although GcMAF is also called Vitamin-D binding protein, the activation of macrophages does not require Vitamin D.

It cannot be said the Gc-MAF cancer cure has gone unheralded. Reuters News covered this developing story in January. But the news story still did not receive top billing nor did it fully elucidate the importance of the discovery, actually made years ago, that the human body is capable of abolishing cancer once its immune system is properly activated.

GcMAF is a naturally made molecule and is not patentable, though its manufacturing process is patent protected. There is no evidence of any current effort to commercialize this therapy or put it into practice. Should such an effective treatment for cancer come into common practice, the income stream from health-insurance plans for every oncology office and cancer center in the world Would likely be reduced to the point of financial insolvency and hundreds of thousands of jobs would be eliminated.

The National Cancer Institute estimates cancer care in the U.S. costs ~$72 billion annually (2004). Furthermore, about $55 billion of cancer drugs are used annually, none which have not significantly improved survival rates throughout the history of their use. If a typical cancer patient had to undergo 30 GcMAF injections at a cost of $150 per injection, that would cost ~$4500, not counting doctor’s office visits and follow-up testing. For comparison, gene-targeted cancer drugs range from $13,000 to $100,000 in cost per year and produce only marginal improvements in survival (weeks to months). [Targeted Oncology 2007 April, 2 (2); 113-19]

Up to this point, the National Cancer Institute is totally silent on this discovery and there is no evidence the cancer care industry plans to quickly mobilize to use this otherwise harmless treatment.

Addendum: Sadly, the treatment you have just read about is not available anywhere. Its inventor is attempting to patent a version of it to profiteer off of it even though there is no need to improve upon the GcMAF molecule - - it worked without failure to completely cure four different types of cancer with no long-term remissions and without side effect. While GcMAF is produced by every healthy adult, there are no centers available to extract it from blood samples and inject it into patients with malignancies. Hopefully, someday, doctors will write protocols to do this and submit them to institutional review boards so GcMAF treatment can be performed on an experimental basis. GcMAF is a naturally-made molecule that cannot be patented. This article was written to reveal that there are proven cancer cures that go unused. Of interest, not one oncologist has requested information about GcMAF since this article was written, while I have been barraged with inquires from cancer patients, their families and some interested physicians who are not cancer doctors.

-Bill Sardi

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By JANE E. BRODY
Published: January 19, 2009
Rochelle and Ian Yankwitt were thrilled when their son, Casey, was born seven years ago, 19 months after the birth of their daughter. But their delight was short-lived. At 7 months, this otherwise happy infant failed to respond to his name or any attempt to engage him with words, his mother recalled in an interview.

Book Is Rallying Resistance to the Antivaccine Crusade (January 13, 2009)
Health Guide: Autism“I thought he was deaf,” Ms. Yankwitt said, but tests showed nothing wrong with his hearing. Instead, at 14 months, Casey received a diagnosis of autism. His parents, both lawyers, wasted no time in setting up early intervention treatments — speech and occupational therapy and special education — as provided by New York State for developmentally disabled children. Ms. Yankwitt, who described Casey as “pretty seriously affected,” left her job to coordinate his endless rounds of treatment.

If not for speech therapy five or more days a week for six years, Ms. Yankwitt is convinced Casey would not have the limited language skills he now has, which enable him to speak in short sentences, make his needs known and share things that excite him.

But, she added, “there is no mistaking Casey for a normal child. He is in constant motion, flaps his arms, is easily frustrated and makes strange noises.”

Ms. Yankwitt read many books and articles by parents claiming that this, that or the other treatment had cured their child’s autism, all anecdotal and based on theories and therapies unproved by scientific study.

“I spent six years hoping that the next thing around the corner would be the one for Casey,” she said.

So far, nothing has made a substantial difference in Casey’s behavior. Still, Ms. Yankwitt said, guided by a pediatrician who specializes in holistic care of children with neurodevelopmental disorders, through trial and error some of the suggested remedies have produced apparent improvements.

The Yankwitts’ many attempts to help their son and, in turn, help themselves are typical of the endless ups and downs faced by families of children with autism, for which there is no documented cure.

A Variable Disorder

According to Laura Schreibman, a psychologist who is the director of the Autism Research Program at the University of California, San Diego, and the author of “The Science and Fiction of Autism” (Harvard University Press, 2005), if anything definitive can be said of the popular therapies for autism, it is that treatments have to be individualized. What works to reduce symptoms in one child may or may not help another.

It is also true that autism is highly variable, with periodic improvements and regressions, and most children receive several therapies at once. So it is difficult to say what makes things better or worse at a given time, Dr. Schreibman said in an interview.

This means that parents like the Yankwitts try one thing after another, often keeping careful records of the latest regimen and its seeming effects on their child’s behavior.

“Parents are afraid of missing what might be effective, so they try everything,” Dr. Schreibman said.

Alternative Therapy

Initially the Yankwitts sought only mainstream therapy for Casey — “we were very afraid of all the alternative treatments,” Ms. Yankwitt said — but a regression he suffered between ages 2 and 3 prompted them to branch out.

Their tests of alternative methods began with a dairy-free diet. “Thirty-six hours later he was like a different kid,” Ms. Yankwitt said. “He made eye contact for the first time. It was as if a layer of smog had peeled off him.”

That was followed by another dietary change: a gluten-free diet, with less obvious results, then “a specific carbohydrate diet to eliminate yeast in his digestive tract,” Ms. Yankwitt said. “These diets are very challenging,” she said. “We carried food for him everywhere he went.”

Next came supplements, introduced one at a time, with daily notes of how Casey reacted to each. In addition to theanine to aid sleep, Casey now takes garlic capsules, calcium, coenzyme Q-10, L-carnitine, taurine, zinc, magnesium, molybdenum, selenium and Nystatin (for yeast), as well as two psychotropic drugs: a mood stabilizer and an antidepressant. He also uses a glutathione cream that is supposed to detoxify his body, a B-12 cream, an intestinal complex to help with digestion, fish oils, curcumin and milk thistle.

At the doctor’s suggestion, Casey underwent a full round of chelation therapy to remove heavy metals from his body that might be damaging his brain, “but it didn’t seem to make a difference in what he was, and so we stopped,” Ms. Yankwitt said.

What she thinks has helped is hyperbaric oxygen therapy purported to reduce inflammation in the brain, which coincided with a significant improvement in Casey’s language skills. But, Ms. Yankwitt conceded, “We don’t know what would have happened if we had done nothing.

Book Is Rallying Resistance to the Antivaccine Crusade (January 13, 2009)
Health Guide: Autism“The most difficult thing for me is constantly hoping something will fix this and being given reason to hope by people you trust,” she added.

In “Defeating Autism: A Damaging Delusion” (Routledge, 2009), Dr. Michael Fitzpatrick, a general practitioner in London whose son is autistic, likened the alternative medicine approach to a return to “medicine’s dark ages.”

Every biomedical intervention, he wrote, “is supported by anecdotes and personal testimonies: it is understandable that parents want to share their experience that their child has made progress, and it is equally understandable that other parents are impressed by success stories.”

Dr. Fitzpatrick continued, “When parents have invested money, time, energy and, above all, hope into a particular treatment, it is natural to seek to attribute any improvement to that treatment.” But, he added, anecdotal examples and wishful thinking are not science.

A Behavioral Approach

The one approach that has been scientifically validated to help, though by no means cure, autistic children is behavioral intervention that mimics the way normal children learn, Dr. Schreibman said. For example, if the child wants to play with a toy car, the therapist holds it and prompts the child to say “car.” If the child makes the “c” sound, he is given the car to play with. The next session may require him to say “car.”

In this way, a behavioral repertoire can be built gradually and systematically to develop behaviors like communication, engagement, social interactions and play skills, Dr. Schreibman said.

“Parents need to learn how to do it,” she said. “It’s a lot of work and it takes a lot of time — maybe 30 to 40 hours a week for a 7-year-old — and the results are not instant, but it does work. But the earlier in a child’s life it is started, the more effective it is likely to be.”

With the increase in awareness of autism and improvements in diagnosis, more children today can get an early start on effective therapy rather than wasting valuable time, effort and money on remedies that lack a scientific basis and proof of effectiveness.

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Breastfeeding can provide infants protection against asthma or respiratory diseases but fast-food intake can negate the benefits, scientists have found.

A number of findings led the University of Alberta researchers to establish links between fast food and asthma, breastfeeding and asthma, and all three together.

“Like other studies, we found that fast-food consumption was associated with asthma,” said study co-author Anita Kozyrskyj, associate professor of paediatrics in the university’s faculty of medicine and dentistry.

The group did not look at why fast food might cause asthma but the authors suggest the high fat content, and high salt levels - which can increase twitchy airways and wheezing - may be to blame.

The research confirmed the findings of many other studies about the benefits of breastfeeding in relation to asthma.

Kozyrskyj found that breastfeeding for too short a time was linked to a higher risk of asthma, or conversely that children exclusively breastfed 12 weeks or longer as infants had a lower risk.

“But this beneficial effect was only seen in children who did not consume fast food, or only occasionally had fast food,” she added. More than half the children in the study ate fast food more than twice a week.

The researchers suggested the prevalence of fast food in today’s society may explain why asthma rates keep rising even though more mothers are breastfeeding, the university said in a release.

Kozyrskyj conducted the study with Allan Becker while at the University of Manitoba. The team looked at about 700 Manitoba children, about 250 of whom had asthma and 475 who did not.

The article appears online in Clinical and Experimental Allergy.

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