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2008-10-22

Feel-good foods

Filed under: In the News — Gay Riley @ 11:25:01

What you eat can affect your mood
By Julie Deardorff | Tribune health and fitness reporter

Chocolate cake is a popular home remedy for depression, but it comes with some unwelcome side effects. Sweet treats don't just pack on the pounds; they give us a sugar high that's inevitably followed by a demoralizing crash.

Still, there's growing recognition in the medical community that the right food choices can improve your mood. Though drugs are often considered the first line of treatment for depression, a dietary change might be all you need, says James Gordon, a psychiatrist who advocates non-drug approaches to depression.

Gordon, a clinical professor at the Georgetown University School of Medicine, believes what we eat affects how we think and feel. "It's a wake-up call to let us know our body is out of balance."

Food can help restore that equilibrium, Gordon wrote in his new book, "Unstuck" (The Penguin Press, $25.95). The trick is knowing which key nutrients to include, and which foods to avoid.

Nutritional changes aren't a magic bullet; they're subtle pieces of a treatment plan that might also include therapy, exercise--one of the most effective depression busters--and stress-reduction techniques.

But "diet can help with virtually any chronic condition" including depression, said registered dietitian Wendy Bazilian, who holds a doctorate in public health. Just remember that major depression might require an integrative approach that uses food in conjunction with other therapies, including medication and counseling. And never abruptly stop taking medication even if you're experiencing side effects such as weight gain and sexual dysfunction; talk to your doctor about tapering down.

Eat more ...

1. Salmon. Fatty, cold-water fish such as salmon contain omega-3 fatty acids, which keep cell membranes pliable and flexible, said neurosurgeon Larry McCleary, founder of a research group that looks at natural ways to treat health issues. It's also in tuna, anchovies and sardines, but since fish fat is also a good place to store heavy metals, pesticides and poylchlorinated biphenyls (PCB), consider plant-based sources, including walnuts, flax seeds, pumpkin seeds and green, leafy vegetables.

2. Oatmeal, soy milk and two scrambled eggs. This meal will give you 500 milligrams of tryptophan, an amino acid that's a precursor for the neurotransmitter serotonin, the brain's feel-good hormone. Many antidepressants are designed to prolong the activity of serotonin in our cells, but you can actually increase the levels by eating carbohydrates (with the exception of fructose, the sugar in fruit), said Judith Wurtman, author of "The Serotonin Power Diet" (Rodale, $24.95).

3. Spinach: Low levels of the B vitamin folate, found in spinach, peas, navy beans, orange juice, wheat germ or avocado, may play a role in depression in some patients, said Brent Bauer, director of the Mayo Clinic's Complementary and Integrative Medicine Program.

4. Vitamin D supplement. Vitamin D has been shown to help with seasonal affective disorder, said Bruce Hollis, professor of pediatrics at the Medical University of South Carolina. It may also have an anti-inflammatory effect and increase the flexibility of cell membranes, making the brain's neurotransmitters work better. While primarily generated after the skin soaks up the sun's ultraviolet B rays, Vitamin D can be obtained from oily fish and supplemented products like cow or soy milk and orange juice.

But Hollis says the recommended daily allowance--200 to 400 international units per day--is far too low. Instead, supplement with 2,000 IU's or higher, especially between October and April for Chicagoans. At these levels, though, food isn't a good option, since you'd have to drink a gallon of milk a day and no one needs those calories, Hollis said.

5. Broccoli and blueberries: When combined with protein in fish, chicken and turkey, high-fiber, non-starchy vegetables help stabilize blood sugar levels, said Jack Challem, author of "The Food-Mood Solution" (Wiley, $24.95). "Our moods usually track with blood sugar levels," Challem said. "When our blood sugar is on the rise right after we eat, most people feel pretty contented. If it goes up too high, people feel sleepy because high blood sugar turns off orexins, a family of neuropeptides involved in feeling alert." Superfruits such as blueberries are high in antioxidants, which are substances that absorb the free radicals produced by stress. Too many free radicals cause wear and tear on the body. Challem recommends green leafy vegetables, broccoli, cauliflower, raspberries, blueberries, blackberries, and kiwifruit.

6. Quinoa. Whole grains, a good source of B vitamins, break down and release sugar slowly, so you don't get high levels of insulin and the ups and down of blood sugar, said Gordon. Quinoa, a seed that is classified as a grain, is considered one of the best sources of protein in the vegetable kingdom. Also try oats, brown rice, or whole wheat bread or pasta.

Eat less ...

Red meat. As you increase omega-3's, try to cut down on the other type of fatty acid, omega-6, which is found in beef. Though essential for brain health, omega-6's are associated with promoting inflammation. Omega-6's are also found in corn and vegetable oils.

Fried foods. Fat is a very important part of a cell's membranes. But trans fats and saturated fats make the membranes rigid; then the neurotransmitters don't work as well. Fried foods, hamburgers, french fries, butter, cheesecake, whole milk and beef are high in saturated fat. A product has trans fats if the ingredients list "partially hydrogenated oils." Food manufacturers are allowed to list amounts of trans fat with less than 0.5 gram as 0 on the Nutrition Facts panel. To avoid it, read labels.

Gas station food. Processed foods contain refined flour and give you high doses of sugar but lack critical nutrients, said Gordon. "You'll often experience a feeling of well-being from the sugar when levels are high, but when it's low you experience a letdown or fatigue." Refined sugars include white table sugar, white flour, high fructose corn syrup. Alcohol and caffeine. Though alcohol is a stimulant in low doses, it also depletes the brain's mood elevator, serotonin. Caffeine blocks the soothing effects of the brain's "feel-good" messenger called GABA (gamma-amino butyric acid) that can calm mood and the digestive tract, said Molly Siple, author of "Eating for Recovery" (Lifelong, $17.95). "Refined foods and caffeine tend to raise the blood glucose," she said. "The drop is a route into depression."

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netnutritionist

2008-10-17

Fructose Sets Table for Weight Gain without Warning

Filed under: In the News — Gay Riley @ 10:46:08

Description
Eating too much fructose can induce leptin resistance, a condition that
can easily lead to becoming overweight when combined with a high-fat,
high-calorie diet, according to a study with rats. The study also found
that leptin resistance can develop silently, that is, with little
indication that it is happening.

Newswise — Eating too much fructose can induce leptin resistance, a
condition that can easily lead to becoming overweight when combined with
a high-fat, high-calorie diet, according to a new study with rats.

Although previous studies have shown that being leptin resistant can
lead to rapid weight gain on a high-fat, high-caloric diet, this is the
first study to show that leptin resistance can develop as a result of
high fructose consumption. The study also showed for the first time that
leptin resistance can develop silently, that is, with little indication
that it is happening.

The study, “Fructose-induced leptin resistance exacerbates weight gain
in response to subsequent high-fat feeding,” was carried out by
Alexandra Shapiro, Wei Mu, Carlos Roncal, Kit-Yan Cheng, Richard J.
Johnson and Philip J. Scarpace, all at the University of Florida College
of Medicine in Gainesville. The study appears in the American Journal of
Physiology – Regulatory, Integrative and Comparative Physiology,
published by The American Physiological Society.

Leptin as regulator

Leptin is a hormone that plays a role in helping the body to balance
food intake with energy expenditure. When leptin isn’t working -- that
is, when the body no longer responds to the leptin it produces -- it’s
called leptin resistance. Leptin resistance is associated with weight
gain and obesity in the face of a high-fat, high-calorie diet.

Obesity has been a growing problem in the U.S. and in other parts of the
world and fructose has been suspected of playing a role. Fructose is the
sugar found in fruit, but it’s not the normal consumption of fruit that
is the problem. Table sugar and high-fructose corn syrup are about 50%
fructose and these ingredients have become increasingly common in many
foods and beverages. With sugar and high-fructose corn syrup being added
to many foods, people now eat much more fructose than ever before.

The University of Florida researchers hypothesized that a high-fructose
diet could lead to leptin resistance, which in turn could lead to
exacerbated weight gain in the face of a high-fat, high-calorie diet, a
typical diet in industrialized countries. To test their hypothesis, the
research team performed a study with two groups of rats. They fed both
groups the same diet, with one important exception: one group consumed a
lot of fructose while the other received no fructose.

Two groups similar over six months

During these six months, there were no differences in food intake, body
weight, and body fat between rats on the high-fructose and the rats on
the fructose-free diets. In addition, there was no difference between
the two groups in the levels of leptin, glucose, cholesterol or insulin
found in their blood. There was only one difference at the end of the
six months: The rats on the high-fructose diet had higher levels of
triglycerides in their blood.

The researchers next tested the animals to see if they were leptin
resistant. They injected all the animals with leptin, to see if they
would respond by eating less. Animals whose leptin response is
functioning normally will lower their food intake. The researchers
discovered that the rats on the high-fructose diet were leptin
resistant, that is, they did not lower their food intake when given
leptin. The no-fructose animals responded normally to leptin by eating less.

This first six months of the study showed that leptin resistance can
develop silently. “Usually, leptin resistance is associated with
obesity, but in this case, leptin resistance developed without obesity,”
Shapiro said. “This was very surprising.”

Role of diet

Having seen that leptin resistance could develop silently, the
researchers next wanted to find out what would happen if they switched
the rats to a high-fat, high-calorie diet -- the kind many Americans
eat. They found that the animals exposed to the high-fructose diet, the
leptin resistant rats, ate more and gained much more weight and fat than
the leptin responsive animals on the fructose-free diet. All told, this
study showed that leptin resistance can:

• develop by eating a lot of fructose
• develop silently, that is, with very little indication it is happening
• result in weight gain when paired with a high fat, calorie dense diet

Scarpace said the study suggests it is the interaction between
consumption of large amounts of fructose-containing foods and eating a
high-fat, high-calorie diet that produces the weight gain. “This study
may explain how the global increase in fructose consumption is related
to the current obesity epidemic,” Shapiro said.

How it happens

Other studies have shown that elevated triglycerides impair the
transport of leptin across the blood brain barrier. The researchers
hypothesize that the elevation in triglycerides produced by fructose
prevented leptin from reaching the brain. If leptin does not reach the
brain, the brain will not send out the signal to stop eating.

“The presence of high fructose alters the way leptin works, fooling the
brain so that it ignores leptin,” Scarpace said. Consumers should be
cautious about what they eat, checking labels to see how much sugar the
items contain, Shapiro said.

The researchers hope to perform future studies to find out if leptin
resistance can be reversed by removing or reducing the fructose content
of the diet.

A fuller audio interview with Drs. Shapiro and Scarpace is available in
Episode 14 of the APS podcast, Life Lines, at http://www.lifelines.tv.

Funding: The National Institutes of Health
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